To summarize the effect of L. reuteri DSM 17938 in the treatment plan for diarrheal disease in children, and analyze the potential of probi otics in preventing the occurrence of diarrheal disease.
9 RCTs:
Maragkoudaki 2018, Shornikova 1997, Dinleyici 2015, Francavilla 2012, Pernica 2017, Dinleyici 2014, Wanke 2012, Urbańska 2016, Kolodziej 2019
L. reuteri DSM 17938
Compared to placebo/no intervention, L. reuteri DSM 17938 significantly reduced the number of patients with diarrhea on day 1 and 2. However, it had no effect on the prevention of diarrhea.
To systematically update evidence on the effectiveness of L. reuteri DSM 17938 in the treatment of AGE in children. The review was initiated as part of the update of the guide lines for the use of probiotics in the management of AGE in children.
4 RCTs:
Dinleyici 2014, Dinleyici 2015, Francavilla 2012, Szymański H 2019
L. reuteri DSM 17938
The addition of L. reuteri DSM 17938 to standard rehydration therapy (compared with placebo or no intervention):
• reduced duration of diarrhoea by 21h
• reduced hospitalization with 13h The findings may inform guideline development groups about the efficacy of L. reuteri DSM 17938 for treating children with AGE.