Infant Colic – Management Infant Colic – Prevention Fifteen Meta-Analyses Supporting the Efficacy in Infant Colic Functional Abdominal Pain (FAP) in Children Meta-Analysis Supporting the Efficacy in Children with FAP Regurgitation in Infants Functional Constipation in Infants and Children Prevention of FGIDs in Infants Functional Constipation in Adults Irritable Bowel Syndrome (IBS)
Reviews with meta-analysis of L. reuteri effects
Ichsan, et al. 2022
Number of Studies
6
Effect in breastfed infants
✔
Effect in mixed fed infants
No statement
Effect in formula-fed infants
More studies needed
Safe to use
✔
Reviews with meta-analysis of L. reuteri effects
Shirazinia R, et al. 2021
Number of Studies
10
Effect in breastfed infants
✔
Effect in mixed fed infants
✔
Effect in formula-fed infants
✔
Safe to use
Not evaluated
Reviews with meta-analysis of L. reuteri effects
Dos Reis Buzzo Zermiani AP, et al. 2021
Number of Studies
8
Effect in breastfed infants
✔
Effect in mixed fed infants
NA
Effect in formula-fed infants
NA
Safe to use
✔
Reviews with meta-analysis of L. reuteri effects
Ellwood J, et al. 2020
Number of Studies
32
Effect in breastfed infants
✔
Effect in mixed fed infants
No statement
Effect in formula-fed infants
No
Safe to use
✔
Reviews with meta-analysis of L. reuteri effects
Skonieczna-Żydecka K, et al. 2020
Number of Studies
16
Effect in breastfed infants
✔
Effect in mixed fed infants
✔
Effect in formula-fed infants
No
Safe to use
✔
Reviews with meta-analysis of L. reuteri effects
Sung V, et al. 2018
Number of Studies
4
Effect in breastfed infants
✔
Effect in mixed fed infants
✔
Effect in formula-fed infants
No
Safe to use
✔
Reviews with meta-analysis of L. reuteri effects
Dryl R, Szajewska H, 2018
Number of Studies
5
Effect in breastfed infants
✔
Effect in mixed fed infants
✔
Effect in formula-fed infants
No
Safe to use
Not evaluated
Reviews with meta-analysis of L. reuteri effects
Gutiérrez-Castrellón P, et al. 2017
Number of Studies
5
Effect in breastfed infants
✔
Effect in mixed fed infants
✔
Effect in formula-fed infants
✔
Safe to use
Not evaluated
Reviews with meta-analysis of L. reuteri effects
Schreck Bird A, et al. 2017
Number of Studies
5
Effect in breastfed infants
✔
Effect in mixed fed infants
✔
Effect in formula-fed infants
More studies needed
Safe to use
✔
Reviews with meta-analysis of L. reuteri effects
Harb T, et al. 2016
Number of Studies
6
Effect in breastfed infants
✔
Effect in mixed fed infants
✔
Effect in formula-fed infants
More studies needed
Safe to use
✔
Reviews with meta-analysis of L. reuteri effects
Xu M, et al. 2015
Number of Studies
5
Effect in breastfed infants
✔
Effect in mixed fed infants
No statement
Effect in formula-fed infants
More studies needed
Safe to use
✔
Reviews with meta-analysis of L. reuteri effects
Urbańska M, Szajewska H, 2014
Number of Studies
3
Effect in breastfed infants
✔
Effect in mixed fed infants
✔
Effect in formula-fed infants
More studies needed
Safe to use
✔
Reviews with meta-analysis of L. reuteri effects
Sung V, et al. 2013
Number of Studies
3
Effect in breastfed infants
✔
Effect in mixed fed infants
No statement
Effect in formula-fed infants
More studies needed
Safe to use
✔
Reviews with meta-analysis of L. reuteri effects
Anabrees J, et al. 2013
Number of Studies
3
Effect in breastfed infants
✔
Effect in mixed fed infants
Possibly
Effect in formula-fed infants
More studies needed
Safe to use
✔