Infant Colic – Management Infant Colic – Prevention Fifteen Meta-Analyses Supporting the Efficacy in Infant Colic Functional Abdominal Pain (FAP) in Children Meta-Analysis Supporting the Efficacy in Children with FAP Regurgitation in Infants Functional Constipation in Infants and Children Prevention of FGIDs in Infants Functional Constipation in Adults Irritable Bowel Syndrome (IBS)
Reference
Indrio F, 2014
Italy
Study Objectives
Investigate if oral supplementation with L. reuteri DSM 17938 during the f irst 3 months of life can reduce the onset of colic, gastroesophageal reflux, and constipation in term newborns, and in addition reduce the socio-economic impact of these conditions
Study Design*
R, DB, PC 90 days Multicentre study
No. of Subjects (dose)
L. reuteri: 238 (1×108 CFU) Placebo: 230
Results
Compared to placebo:
• Daily administration of L. reuteri early in life reduced daily inconsolable type of crying, frequency of regurgitation, and incidence of functional constipation in the first 3 months of life
• Private and public costs for the management of these condi tions were significantly reduced for infants receiving L. reuteri